Long-term creatine intake is beneficial to muscle performance during resistance training

Vandenberghe, Goris, Van Hecke, Van Leemputte, Vangerven & Hespel (1997) · Journal of Applied Physiology

Topics: Women's Health, Strength & Power, Muscle & Body Composition

  • Study type: Randomized trial
  • Population: Sedentary young women
  • Sample: n=19
  • Dose: 20 g/day loading, then 5 g/day
  • Duration: 10 weeks
  • Published: 1997

What the study found

A foundational trial in women. Previously untrained women who took creatine during 10 weeks of resistance training gained significantly more muscle strength and fat-free mass than those on placebo, and the gains persisted through a detraining period.

Key findings

  • Greater increases in maximal strength and fat-free mass versus placebo.
  • Muscle creatine and phosphocreatine rose significantly.
  • Benefits were maintained during a subsequent detraining phase.

The practical takeaway

Creatine works just as well in women as in men — an important counter to the myth that it's a men-only supplement.

View the original study on PubMed