Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?

Antonio, Candow, Forbes, Gualano, Jagim, Kreider, Rawson, Smith-Ryan, VanDusseldorp, Willoughby & Ziegenfuss (2021) · Journal of the International Society of Sports Nutrition

Topics: Safety & Kidney, Muscle & Body Composition, Dosing & Loading

  • Study type: Expert review
  • Population: General population
  • Dose: 3-5 g/day
  • Duration: N/A
  • Published: 2021

What the study found

A myth-busting consensus paper by leading creatine scientists. It systematically debunks common misconceptions — that creatine causes hair loss, kidney damage, dehydration, cramping, or is only for men — and clarifies what the evidence actually supports.

Key findings

  • No good evidence that creatine causes hair loss, kidney damage, or dehydration.
  • Creatine does not cause cramping; if anything it may reduce it.
  • Weight gain is mostly intramuscular water and lean mass, not fat.

The practical takeaway

Most 'creatine side effects' you've heard are myths — this paper is the reference for setting the record straight.

View the original study on PubMed